![]() Long-term and frequent use of capsaicin cream desensitizes secreting fibers of substance P and reduces the substance secretion, thus relieving pain ( 22, 23). The use of these materials is because of such effects in combinations of these natural elements ( 20). In a study, therapeutic effects of Capsanthin were shown in diabetic neuropathy, osteoarthritis and herpetic neuralgia ( 21). Capsaicin containssubstances like Capsanthin, henceexpected to have mutual effects of topical irritant ( 20). So far, many natural materials such as capsaicin have been used in traditional medicine to relieve low back pain. The use of medicinal plants in Egypt, Indian, China and Iran dates back more than other countries ( 19). In the recent years, herbal therapy has been more considered as one of the complementary medicine aspects ( 18). Infact, many complementary medicine majors such as acupuncture and herbal therapy are under the banner of natural medicine ( 17). The use of herbal medicines is apart of holistic medicine and its application along with modern medicine is effective in improving these patients ( 16). Available treatments include proper training, physical activity without doing heavy work, medical treatments including non-steroidal anti-inflammatory drugs, physiotherapy, use of medical belts, acupuncture and herbal medicines ( 14, 15). ![]() Many different treatment methods have been used to treat low back pain in patients with inter-vertebral disc herniation. stated that many patients with chronic pain have personality disorders, drug dependency, instability in family relationships and career incompatible ( 13). Pain affects these patients’ health, performance and quality of life chronic pains would cause physical and mental health involvement in adults and children ( 12). The most common clinical display of the disease is low back pain and the phenomenon is because of segmentalannulus innervation in lumbar disc, which is the most sensitive anatomically structure to pain ( 10, 11). The destructive cause of lumbar disc is complex and not fully explained, so that its cause would be considered asa multifactorial disorder including a number of genetic and environmental factors and their inter actions ( 9). Inter-vertebral disc acts as a joint between the vertebrae and the shock-absorbing, in severe and sudden pressure on the spine, fibrous fibers of the outer layer of inter-vertebral disc would be torn and the central gelatinous disc substance would be herniated outward called inter-vertebral disc herniation ( 8). Its prevalence is 7 - 37% indifferent countries and 8.20% in Iran, but there is no exact statistics regarding its prevalence rate in total ( 7). Prevalence of disc herniation is more common in men than women ( 6). Inter-vertebral disc herniationis one of the common causes of disease, especially in the third and fourth decades of life ( 4) and a major cause of function limitation and impairment of quality of life and chronic disability in both sexes ( 5). Low back pain is one of the most common health problems in America and other countries of the world and is the most common cause of disability and absence from work ( 1- 3). Therefore, the ointment can be recommended in the treatment of low back pain caused by inter-vertebral disc herniation. Capsaicin cream has beneficial effects on pain relieving and reducing analgesic use in patients with inter-vertebral disc herniation.
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